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. 2015 Jul 15;3:26–31. doi: 10.1016/j.bbrep.2015.07.008

Fig. 2.

Fig. 2

Evaluation of KIF14 expression in primary OSCCs. (A, B) Representative IHC results for KIF14 protein in primary OSCCs and normal oral tissue (scale bars, 10 μm). Strong KIF14 immunoreactivity is detected in the nuclei of primary OSCCs; normal oral tissues show almost negative immunostaining. (C) The state of KIF14 protein expression in primary OSCCs (n=104) and the normal counterparts. The KIF14 IHC scores for normal oral tissues and OSCCs range from 10 to 135 (median, 65) and 70 to 230 (median, 150), respectively. KIF14 protein expression levels in OSCCs are significantly (P<0.05, Mann–Whitney's U test) higher than in normal oral tissues. (D) Youden Index analysis shows that the optimal cutoff point is 95.0. (E) ROC curve analysis shows that the optimal cutoff point is 95.0.