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. Author manuscript; available in PMC: 2017 Nov 3.
Published in final edited form as: Arthritis Rheumatol. 2016 Aug;68(8):1856–1868. doi: 10.1002/art.39657

Figure 3. Btk-deficiency reduces mature B cell subsets in K/BxNs.

Figure 3

A) Representative flow plots for Btk-sufficient (left) and Btk-deficient (right) K/BxN, showing gating scheme for B cell subsets. Cells are gated as single, live, B220+ lymphocytes. B) Quantification of B cell subsets in Btk-sufficient (circles, n=6) or –deficient (squares, n=6) K/BxN by percentage of total IgM+IgD+ B cells (left) and by total cell number (right). **p≤0.01, ***p≤0.001, as calculated by the Holm-Sidak method of multiple T tests.