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. 2017 Nov 2;14:213. doi: 10.1186/s12974-017-0988-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Bone cancer in tibia induced mechanical allodynia of hindpaw. a Experimental paradigms. b Bone cancer resulted in prominent decrease in the PWTs of ipsilateral hind paw on POD 5 to 19 and also of the contralateral hind paw on POD 7 to 19. n = 8 per group, *p < 0.05 vs. sham-ipsilateral; ^# p < 0.05 vs. BCP-contralateral