Table 1.
Summary of the consortium data sets used for stages 1, 2 and stage 3. Data are from the Genetic and Environmental Risk for Alzheimer’s Disease (GERAD)/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease (PERADES) Consortium, the Alzheimer’s Disease Genetic Consortium (ADGC), the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) and the European Alzheimer’s disease Initiative (EADI)(Supplement 1).
| Consortium | N Controls | N Cases | N Total | |
|---|---|---|---|---|
| Stage 1 | GERAD/PERADES | 2974 | 6000 | 8974 |
| ADGC | 7002 | 8706 | 15708 | |
| CHARGE | 8101 | 1391 | 9492 | |
| Total | 18077 | 16097 | 34174 | |
|
| ||||
| Stage 2 | GERAD/PERADES genotype | 5049 | 4049 | 9098 |
| CHARGE-genotype | 1839 | 1434 | 3273 | |
| CHARGE-in silico | 3246 | 722 | 3968 | |
| EADI-genotype | 11787 | 7836 | 19623 | |
| Total | 21921 | 14041 | 35962 | |
|
| ||||
| Stage 3 | ADGC-in silico | 8345 | 6652 | 14997 |
|
| ||||
| Stage 1 + 2 + 3 | ||||
| Total | 48402 | 37022 | 85133 | |