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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Melanoma Res. 2017 Dec;27(6):527–535. doi: 10.1097/CMR.0000000000000388

Table 1.

Enriched GO terms (GOTERM_BP_ALL) for the top 250 up-regulated (A) and 250 down-regulated (B) genes in V600K tumors compared to V600E tumors

(A) Top 250 up-regulated genes in V600K tumors
GO Term No. genes in pathway Benjamini-Hochberg procedure adjusted p-value
Cofactor metabolic process 20 9.8E-04
Coenzyme metabolic process 16 1.4E-02
Carboxylic acid metabolic process 27 1.1E-02
Oxoacid metabolic process 27 9.4E-03
Organic acid metabolic process 28 1.2E-02
(B) Top 250 down-regulated genes in V600K tumors
GO Term No. genes in pathway Benjamini-Hochberg procedure adjusted p-value
Anatomical structure morphogenesis 54 3.7E-03
Embryonic skeletal system development 10 9.7E-03
Embryonic skeletal system morphogenesis 9 6.5E-03
morphogenesis of an epithelium 19 8.1E-03
Embryonic organ morphogenesis 15 7.0E-03