Table 3.

Top 15 differentially down-regulated microRNAs in V600K tumors compared to V600E tumors. A total of 1,046 microRNAs were analyzed by TCGA.

miRNA	p-value	Predicted¶ or known to regulate c-Kit expression
hsa-mir-222	0.0004	Known
hsa-mir-125b-1	0.0012	No
hsa-mir-34b	0.0017	Predicted
hsa-mir-34c	0.0023	Known
hsa-mir-10b	0.0032	No
hsa-mir-664	0.0032	No
hsa-mir-1271	0.0055	No
hsa-mir-708	0.0056	No
hsa-mir-100	0.0058	No
hsa-mir-653	0.0077	No
hsa-mir-19b-2	0.0084	Known
hsa-mir-196b	0.0093	No
hsa-mir-148a	0.0097	Known
hsa-mir-10a	0.0117	No
hsa-mir-574	0.0120	No

^¶based on prediction by microRNA.org. See text for references.