Table 4B.

GNA11, KIT, and PTEN mutations and KIT copy number alterations in V600K tumors in relation to c-Kit protein expression.

Name	Mutation			Copy No. Alteration	c-Kit expression
	GNA11	KIT	PTEN	KIT_cnv
TCGA-BF-A3DL-01	wt	wt	wt	0	2.6437
TCGA-BF-A3DM-01	wt	wt	H92Y	0	−0.3460
TCGA-BF-A5EQ-01	wt	wt	wt	0	2.7293
TCGA-DA-A1I0-06	wt	F182_splice	wt	0	0.9899
TCGA-DA-A3F8-06	wt	Y200S	R301C;H92Y	−1	0.4071
TCGA-EB-A3XB-01	wt	wt	R301C	1	0.5543
TCGA-EE-A183-06	wt	wt	wt	0	n/a
TCGA-EE-A20H-06	wt	wt	wt	0	n/a
TCGA-EE-A29E-06	wt	R311*	wt	0	1.4094
TCGA-EE-A2GB-06	wt	wt	wt	1	n/a
TCGA-EE-A2GT-06	G8S	wt	wt	−1	1.2554
TCGA-EE-A2ME-06	wt	wt	wt	0	n/a
TCGA-ER-A19J-06	wt	wt	wt	0	−0.9046
TCGA-ER-A19K-01	wt	wt	wt	0	2.8772
TCGA-ER-A42L-06	R132C	wt	wt	−1	1.1497
TCGA-FS-A1ZC-06	wt	wt	R301C	0	−0.9696
TCGA-IH-A3EA-01	R132C	wt	wt	0	0.7967

‘n/a’ denotes no data from TCGA. Mutation and copy number alteration data are from [2]. The three tumors with the highest c-Kit expression are highlighted.