Table 3. Fitted Bayesian log-normal survival model for overall survival (N=45).
Values in the column “Probability of a Beneficial Effect” close to either 1 or 0 correspond to a significant effect. Higher number of administered cycles of azacitidine, but not dose, was associated with improved survival.
Variable | Mean | SD | Posterior 95% Credible Interval | Probability of a Beneficial Effect | |
---|---|---|---|---|---|
2.5% | 97.5% | ||||
| |||||
Intercept | 1.474 | 0.337 | 0.787 | 2.174 | - |
log(BM blast) | −0.108 | 0.062 | −0.253 | −0.003 | 0.022 |
Number of chemotherapy regimens >=2 (versus 0, 1) | −0.334 | 0.187 | −0.707 | −0.005 | 0.023 |
Number of comorbidities | −0.086 | 0.041 | −0.176 | −0.013 | 0.010 |
Azacitidine dose | 0.006 | 0.009 | −0.010 | 0.026 | 0.716 |
Number of cycles | 0.118 | 0.074 | −0.029 | 0.263 | 0.946 |
r | 0.676 | 0.272 | 0.247 | 1.293 | - |