Table 7.
Posterior mean and standard deviation of the per-administration hazard parameters in the Bayesian model for the probability of toxicity as a function of per-administration dose (PAD) and number of cycles.
Area a |
Days to Peak of Hazard b |
Days from Peak of Hazard to End c |
Duration (Days) b + c |
|
---|---|---|---|---|
PAD | Mean (Std Dev) | Mean (Std Dev) | Mean (Std Dev) | Mean (Std Dev) |
8 | 0.0058 (0.0034) | 14.5 (24.1) | 8.7 (12.8) | 23.2 (27.8) |
16 | 0.0095 (0.0041) | 14.9 (22.9) | 14.4 (21.6) | 29.4 (31.5) |
24 | 0.0138 (0.0049) | 11.7 (25.7) | 20.3 (38.9) | 32.0 (47.3) |
32 | 0.0163 (0.0054) | 15.9 (12.4) | 31.3 (29.4) | 47.3 (26.6) |
40 | 0.0295 (0.0160) | 14.0 (11.9) | 32.0 (29.0) | 46.0 (26.5) |