Table 1.
Three‐Month Outcome of Acute Ischemic Stroke Patients
| Total (N=33 530) | Modified Rankin Scale | P Value | ||
|---|---|---|---|---|
| 0 to 2 (N=17 842) | 3 to 6 (N=15 688) | |||
| Mean age, y | 68.8±13.3 | 65.1±12.9 | 73.0±12.4 | <0.0001 |
| Age ≥65 y | 21 425 (63.9%) | 9423 (52.8%) | 12 002 (76.5%) | <0.0001 |
| Female sex | 13 622 (40.6%) | 6156 (34.5%) | 7466 (47.6%) | <0.0001 |
| Stroke risk factors | ||||
| Hypertension | 24 640 (73.5%) | 12 911 (72.4%) | 11 729 (74.8%) | <0.0001 |
| Diabetes mellitus | 12 293 (36.7%) | 6282 (35.2%) | 6011 (38.3%) | <0.0001 |
| Previous stroke or TIA | 8782 (26.2%) | 4090 (22.9%) | 4692 (29.9%) | <0.0001 |
| Coronary artery disease | 4507 (13.4%) | 1998 (11.2%) | 2509 (16.0%) | <0.0001 |
| Atrial fibrillation | 4363 (13.0%) | 1505 (8.44%) | 2858 (18.2%) | <0.0001 |
| Dyslipidemia | 14 484 (43.2%) | 7959 (44.6%) | 6525 (41.6%) | <0.0001 |
| Current smoker | 8047 (24.0%) | 4716 (26.4%) | 3331 (21.2%) | <0.0001 |
| Carotid stenosis | 2937 (8.8%) | 1287 (7.2%) | 1650 (10.5%) | <0.0001 |
| TOAST classification | <0.0001 | |||
| Large artery atherosclerosis | 9315 (27.8%) | 4376 (24.5%) | 4939 (31.5%) | |
| Small vessel occlusion | 12 747 (38.0%) | 8759 (49.1%) | 3988 (25.4%) | |
| Cardioembolism | 4002 (11.9%) | 1571 (8.8%) | 2431 (15.5%) | |
| Specific etiology | 574 (1.7%) | 257 (1.4%) | 317 (2.0%) | |
| Undetermined etiology | 6892 (20.6%) | 2879 (16.1%) | 4013 (25.6%) | |
| Characteristics on admission | ||||
| NIHSS | 6.2±8.1 | 4.6±6.7 | 7.9±9.1 | <0.0001 |
| Systolic blood pressure, mm Hg | 160.2±31.1 | 160.8±30.1 | 159.6±32.1 | 0.0005 |
| Diastolic blood pressure, mm Hg | 87.9±19.5 | 89.0±18.9 | 86.6±20.1 | <0.0001 |
| PP, mm Hg | 72.4±23.8 | 71.8±22.8 | 73.0±24.8 | <0.0001 |
| Thrombolyric therapy | 1070 (3.2%) | 427 (2.4%) | 643 (4.1%) | <0.0001 |
Values are number (percentage) or mean (SD). NIHSS indicates National Institutes of Health Stroke Scale; PP, pulse pressure; TIA, transient ischemic attack; TOAST, Trial of ORG 10172 in Acute Stroke Treatment.