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. 2017 May 26;6(6):e005152. doi: 10.1161/JAHA.116.005152

Table 2.

Electrocardiographic Characteristics Before and After Initiation of Disopyramide (n=100)

Pre‐Disopyramide Post‐Disopyramide (300 mg) Δ P Value
Heart rate, bpm ±SD 61±9 65±11 4±9.8 0.016
PR, ms ±SD 168±32 181±27 13±28 0.001
QRS, ms ±SD 105±19 109±22 4±10 0.224
QT, ms ±SD 424±37 435±37 10±28 0.038
QTcB, ms ±SD 426±33 450±32 24±27 0.0001
QTcF, ms ±SD 425±31 445±29 19±23 0.0001
QTcF
≥460 ms 16 (16) 33 (33)
460 to 479 ms 12 (12) 21 (21)
480 to 499 ms 3 (3) 8 (8)
≥500 ms, n (%) 1 (1) 4 (4)

QTcB indicates corrected QT interval, Bazett's formula; QTcF, corrected QT interval, Fridericia's formula.