Figure 4.

Core temperature changes in response to interventions associated with the tail‐cuff technique as determined by telemetry. Interventions took place within the following periods: presence of the researcher in the room was between 0 and 3 minutes, cage was moved at 0 minute, handling took place between 0 and 1 minute, restraint with and without heating and tail‐cuff started at 0 and lasted until 15 minutes. Values are mean±SEM for 4 animals, ^$ P<0.05 for presence in the room, ^{^^^} P<0.001 moving cage, ^&&& P<0.001 restraint without heating, ***P<0.001 for handling, restraint with heating, and tail‐cuff intervention compared to baseline measurements using 2‐way‐repeated‐measures ANOVA and Bonferroni post‐hoc comparison test.