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. 2017 Jun 27;6(6):e005204. doi: 10.1161/JAHA.116.005204

Figure 8.

Figure 8

Correlation analysis of blood pressure recordings made by telemetry and tail‐cuff techniques. The correlations shown are as follows: in the same mouse simultaneously (A and B); nonsimultaneously, with telemetry readings taken before the mouse was disturbed (C and D); differences in the recordings made by tail‐cuff and telemetry simultaneous systolic (E) and diastolic (F) blood pressure vs telemetry. Data show systolic (SBP) or diastolic (DBP) blood pressure at baseline (clear circles), following vehicle infusion via minipump (filled triangles) or angiotensin II (AngII) infusion via minipump (crosses). Pearson correlations are as follows: (A) Pearson r=0.40, 0.88 and 0.74 at baseline, following vehicle or AngII infusion, respectively, r²=0.16, 0.77 and 0.55, slope=0.45±0.09, 0.70±0.07, 1.04±0.06 for each group, respectively. For the combined groups, Pearson r=0.76 and r²=0.57. B, DBP as measured simultaneously by the 2 techniques before (baseline), and after vehicle or AngII infusion: Pearson r=0.23, 0.88, 0.68, r²=0.05, 0.74, 0.46, respectively, for each group; for the combined data set, Pearson r=0.60, r²=0.44. C, SBP acquired nonsimultaneously by the 2 techniques: Pearson r=0.46, 0.27, 0.25, r²=0.21, 0.08, and 0.06 for baseline, vehicle, and AngII groups, respectively. For the combined data set, Pearson r=0.51; r²=0.26. D, DBP acquired nonsimultaneously by the 2 techniques, Pearson r=0.25, −0.15, 0.36, r²=0.06, 0.02, 0.13; for the combined data set, Pearson r=0.47, r²=0.22. E, Correlation analysis of the difference in SBP as recorded by both techniques (tail‐cuff—telemetry) vs central BP as recorded by telemetry: Pearson r=−0.43, −0.61 and 0.06, r²=0.21, 0.37, >0.01 for baseline, vehicle, and AngII groups, respectively. F, Correlation analysis of the difference in DBP as recorded by both techniques (tail‐cuff—telemetry) vs central BP as recorded by telemetry: Pearson r=−0.36, −0.67, and >0.01, r²=0.13, 0.45, >0.01 for baseline, vehicle, and AngII groups, respectively. Each data point represents 1 of the 399 pairs of simultaneous measurements (A and B), of which: baseline, 141 pairs, following vehicle, 41 pairs, or AngII infusion, 216 pairs; 437 nonsimultaneous measurements (C and D), of which: baseline, 161 pairs of recordings, following vehicle, 54 pairs, or AngII infusion, 222 pairs of data, made by telemetry and tail‐cuff in 12 mice.