Comparison of recordings acquired simultaneously and nonsimultaneously by the 2 techniques at baseline and in the angiotensin II (AngII) hypertension model. A, SBP measured by telemetry before the animals were disturbed (gray bar) and during tail‐cuff protocol (filled bar), compared with the SBP readings obtained by the tail‐cuff technique (clear bar) in the same mouse without AngII infusion (n=6); ***P<0.001 telemetry recordings during the tail‐cuff protocol vs tail‐cuff recordings and telemetry undisturbed. B, SBP and (C) DBP determined by the 2 techniques before and following AngII infusion: measurements by telemetry before the animals were disturbed (gray triangles), during the tail‐cuff protocol (filled squares), and measurements by the tail‐cuff technique (clear circles). Values are mean±SEM for 8 mice on days −3, −2, 9, and 11, 4 mice on days 3 and 5; ***P<0.001 vs telemetry recordings during the tail‐cuff protocol repeated measures‐ANOVA). DBP indicates diastolic blood pressure; SBP, systolic blood pressure.