Table 8.
Sensitivity Analysis of Hazard Ratios Estimated by Propensity Score Method
| METS Definition | Outcome | METS Status | Propensity Score Regression Adjustment | Propensity Score Weighting | ||
|---|---|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |||
| CDS | Stroke | Neither | 1 | 1 | ||
| METS only | 0.99 (0.65–1.52) | 0.97 | 1.02 (0.70–1.49) | 0.92 | ||
| DM only | 3.66 (2.61–5.14) | <0.001 | 3.09 (2.40–3.99) | <0.001 | ||
| Both | 3.69 (2.32–5.86) | <0.001 | 2.88 (2.09–3.97) | <0.001 | ||
| Composite end point | Neither | 1 | 1 | |||
| METS only | 0.99 (0.65–1.52) | 0.99 | 1.02 (0.70–1.49) | 0.92 | ||
| DM only | 3.70 (2.64–5.18) | <0.001 | 3.10 (2.41–4.00) | <0.001 | ||
| Both | 3.87 (2.45–6.12) | <0.001 | 2.96 (2.15–4.07) | <0.001 | ||
| Ischemic stroke | Neither | 1 | 1 | |||
| METS only | 1.01 (0.66–1.55) | 0.95 | 1.05 (0.72–1.53) | 0.80 | ||
| DM only | 3.74 (2.66–5.27) | <0.001 | 3.14 (2.43–4.06) | <0.001 | ||
| Both | 3.82 (2.40–6.08) | <0.001 | 2.96 (2.14–4.08) | <0.001 | ||
| IDF | Stroke | Neither | 1 | 1 | ||
| METS only | 1.21 (0.76–1.94) | 0.42 | 0.91 (0.61–1.36) | 0.64 | ||
| DM only | 3.80 (2.68–5.38) | <0.001 | 2.54 (2.09–3.10) | <0.001 | ||
| Both | 4.76 (3.04–7.46) | <0.001 | 2.53 (1.87–3.44) | <0.001 | ||
| Composite end point | Neither | 1 | 1 | |||
| METS only | 1.21 (0.76–1.94) | 0.42 | 0.91 (0.61–1.36) | 0.64 | ||
| DM only | 3.80 (2.68–5.38) | <0.001 | 2.54 (2.09–3.10) | <0.001 | ||
| Both | 5.02 (3.23–7.82) | <0.001 | 2.61 (1.93–3.54) | <0.001 | ||
| Ischemic stroke | Neither | 1 | 1 | |||
| METS only | 1.25 (0.78–2.00) | 0.36 | 0.92 (0.62–1.38) | 0.69 | ||
| DM only | 3.88 (2.73–5.52) | <0.001 | 2.35 (1.91–2.88) | <0.001 | ||
| Both | 4.96 (3.16–7.79) | <0.001 | 2.57 (1.89–3.49) | <0.001 | ||
CDS indicates Chinese Diabetes Society; DM, diabetes mellitus; HR, hazard ratio; IDF, International Diabetes Foundation; METS, metabolic syndrome.