Table 2.

Cox Regression Analyses (Stratified on Year of Birth) for Body Size at Birth and Incident AF

	Model 1a				Model 2b
	HR	95% CI	P Value	Individuals (Cases)	HR	95% CI	P Value	Individuals (Cases)
All
Birth weightc
<2500 g	1.24	0.84 to 1.86	0.28		1.42	0.93 to 2.19	0.10
2500 to 2999 g	1.19	0.99 to 1.45	0.07		1.22	1.00 to 1.50	0.06
3000 to 3999 g	1				1
≥4000 g	1.26	1.03 to 1.54	0.02		1.12	0.90 to 1.39	0.33
Birth length, per cm increase	1.03	0.99 to 1.07	0.17	12 769 (865)	1.00	0.96 to 1.04	0.94	11 620 (788)
Men
Birth weightd				6707 (611)				6044 (547)
<2500 g	1.11	0.68 to 1.80	0.69		1.38	0.82 to 2.30	0.22
2500 to 2999 g	1.07	0.84 to 1.38	0.59		1.06	0.81 to 1.38	0.70
3000 to 3999 g	1				1
≥4000 g	1.25	0.99 to 1.57	0.06		1.11	0.86 to 1.42	0.42
Birth length, per cm increase	1.06	1.01 to 1.11	0.01	6658 (603)	1.04	0.99 to 1.09	0.17	6000 (541)
Women
Birth weighte				6169 (264)				5576 (241)
<2500 g	1.70	0.85 to 3.43	0.14		1.64	0.75 to 3.62	0.22
2500 to 2999 g	1.44	1.06 to 1.96	0.02		1.54	1.12 to 2.12	0.008
3000 to 3999 g	1				1
≥4000 g	1.35	0.88 to 2.08	0.17		1.19	0.75 to 1.58	0.45
Birth length, per cm increase	0.95	0.88 to 1.02	0.18	6111 (262)	0.92	0.86 to 1.00	0.05	5531 (239)

AF indicates atrial fibrillation; BMI, body mass index; HR, hazard ratio.

^aAdjusted for socioeconomic status at birth, gestational age, and sex (where applicable).

^bAdjusted for Model 1+maternal BMI.

^c P for quadratic trend=0.01 in Model 1 and 0.048 in Model 2.

^d P for quadratic trend=0.08 in Model 1 and 0.17 in Model 2.

^e P for quadratic trend=0.13 in Model 1 and 0.31 in Model 2.