Figure 2.

Early treatment with CM352 reduced hematoma after intraparenchymal injection of collagenase in rats. A, Analysis of hematoma volume was performed by T2‐weighted magnetic resonance image. Saline (n=6) or CM352 (1 mg/kg, n=6) was administered at 1 hour after collagenase injection. B, Hematoma volume was measured at 1 hour, 3 hours, 24 hours, and 14 days after collagenase injection. C, Analysis of hematoma expansion. Data are shown as mean±standard deviation or median [interquartile range]. Differences from control group are denoted as *P<0.05; **P<0.01. White boxes indicate saline controls; shaded boxes, CM352 treatment.