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MMP Inhibitory Activity (IC50) of CM352 and GM6001 (as Reference Compound)
| CM352 | GM6001 | |
|---|---|---|
| MMP‐2 | 8.4 nmol/L | 1.1 nmol/L |
| MMP‐3 | 15.0 nmol/L | 20.7 nmol/L |
| MMP‐9 | 10.0 nmol/L | 0.3 nmol/L |
| MMP‐7 | 16.0 μmol/L | 9.0 nmol/L |
| MMP‐10 | 12.0 nmol/L | 31.7 nmol/L |
| MMP‐12 | 7.6 nmol/L | 1.2 nmol/L |
MMP indicates matrix metalloproteinase.
