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Reduced JPH2 expression is associated with right ventricular hypertrophy and RV dysfunction in vivo. JPH2 levels are inversely associated with diastolic RVFW thickness (r=−0.58, P=0.002) (A) and are positively correlated with RV function as determined by percentage change in RVFW thickness (r=0.67, P=0.0003) (B) and TAPSE (r=0.54, P=0.005) (C). AU indicates arbitrary units; JPH2, junctophilin‐2; RVFW, right ventricle free wall; TAPSE, tricuspid annular plane systolic excursion.
