Figure 5.

Case illustration of a study subject. A 32-year-old male smoker with migraine, diabetes, and hyperlipidemia presented with last known normal time of 0830 with an NIH Stroke Scale of 18 (aphasia, right hemisensory loss, and right hemiparesis). The subject received intravenous t-PA. CTA (a) and angiography demonstrated a left ICA distal occlusion extending to the MCA, with a CTA collateral score of 1. He underwent TICI 3 recanalization via thrombectomy approximately 3.5 h after last known normal (b). IA verapamil was administered per study protocol. Postoperative MRI demonstrated a small stroke (34.2 cc) limited to the basal ganglia (c). The subject was discharged to acute rehabilitation, and had an mRS score of 1 at 90 days.