Table 2.
Comparisons of neuropsychological tests across diagnostic groups and families (age, sex, and education covariates)
| Test/index | Control (0) (N= 15) | Family member (1) (N= 23) | Scz (2) (N= 18) | Main effect Diagnosis | Main effect Family | Interaction | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| M | SD | M | SD | M | SD | F | Sig | F | Sig | F | Sig | |
| Raw VIQ | 40.87 | 9.43 | 34.52 | 9.08 | 31.06 | 8.68 | 1.46 | 0.24 | 0.62 | 0.84 | 0.59 | 0.63 |
| Raw PIQ | 28.73 | 4.98 | 23.39 | 6.53 | 21.78 | 6.46 | 1.93 | 0.18 | 0.66 | 0.81 | 2.18 | 0.11 |
| Raw FSIQ | 69.60 | 13.61 | 57.91 | 13.86 | 53.39 | 14.48 | 1.60 | 0.22 | 0.51 | 0.93 | 1.47 | 0.24 |
| Raw VCI | 20.80 | 6.16 | 16.87 | 4.53 | 16.28 | 5.00 | 0.32 | 0.58 | 1.25 | 0.29 | 0.30 | 0.83 |
| Raw POI | 19.27 | 2.99 | 14.48 | 4.63 | 13.61 | 4.42 | 0.92 | 0.35 | 0.62 | 0.85 | 2.52 | 0.08 |
| Raw WMI | 19.80 | 4.21 | 16.91 | 4.62 | 13.94 | 4.78 | 4.16 | 0.05b | 0.56 | 0.90 | 1.04 | 0.39 |
| Raw PSI | 10.67 | 3.39 | 8.43 | 3.92 | 6.89 | 3.55 | 2.55 | 0.12 | 0.60 | 0.87 | 0.20 | 0.90 |
| BNT total | 44.13 | 6.42 | 36.26 | 7.49 | 34.56 | 8.40 | 1.32 | 0.26 | 0.60 | 0.87 | 0.28 | 0.84 |
| Perri Short | 99.36 | 24.48 | 80.21 | 24.36 | 84.62 | 30.22 | 0.34 | 0.56 | 0.82 | 0.66 | 0.28 | 0.84 |
| Perri Long | 105.60 | 36.84 | 93.00 | 18.76 | 91.26 | 33.65 | 0.15 | 0.71 | 2.42 | 0.02* | 1.39 | 0.26 |
| Trails A | 76.20 | 23.33 | 116.52 | 88.17 | 127.22 | 66.16 | 0.57 | 0.45 | 0.27 | 1.00 | 0.27 | 0.85 |
| Trails B | 246.80 | 113.12 | 287.83 | 162.31 | 332.78 | 194.64 | 4.14 | 0.05b | 0.67 | 0.80 | 0.65 | 0.59 |
| Stroop Int | −1.66 | 9.68 | 0.35 | 8.71 | 0.92 | 7.49 | 0.23 | 0.64 | 1.87 | 0.06 | 0.14 | 0.93 |
| COWA PAM | 29.60 | 9.00 | 29.04 | 9.81 | 26.28 | 11.75 | 1.33 | 0.26 | 0.66 | 0.82 | 0.12 | 0.95 |
| COWA Anim | 16.33 | 3.31 | 15.13 | 4.20 | 13.00 | 3.61 | 3.06 | 0.09 | 1.25 | 0.29 | 0.87 | 0.47 |
| Laterality | 59.42 | 72.35 | 35.44 | 70.69 | 9.25 | 68.52 | 1.55 | 0.22 | 0.90 | 0.58 | 0.52 | 0.67 |
| WCST Errors | 61.80 | 23.47 | 68.00 | 20.30 | 59.00 | 19.62 | 0.87 | 0.36 | 1.55 | 0.14 | 0.82 | 0.49 |
| Categories | 2.60 | 2.13 | 1.78 | 1.88 | 2.33 | 1.64 | 0.53 | 0.47 | 1.37 | 0.22 | 0.86 | 0.47 |
Sig, at P < 0.05 after Bonferroni correction: a=0,1 b=0,2 c =1,2.
BNT, Boston naming test total correct responses; COWA anim, controlled oral word association total number of animal names; COWA PAM, Controlled Oral Word Association total correct responses beginning with P, A and M; Laterality index, laterality index from Purdue Pegboard Test; Perri Long, test de Memoria de perri long delayed recall; Perri Short, test de memoria de perri immediate recall; Raw FSIQ, WAIS-III full scale IQ total raw score; Raw PIQ, WAIS-III performance IQ total raw score; Raw POI, WAIS-III perceptual organization index total raw score; Raw VCI, WAIS-III verbal comprehension index total raw score; Raw VIQ, Wechsler Adult Intelligence Scale, 3rd Revision (WAIS-III) verbal IQ total raw score; Raw WMI,WAIS-III working memory index total raw score; Raw PSI, WAIS-III processing speed index total raw score; Stroop int, stroop interference score; Trails A, trail making test part A completion time; Trails B, trail making test part B completion time; WCST categories, Wisconsin Card Sort test total categories completed; WCST errors, total number errors on Wisconsin Card Sort Test.