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. Author manuscript; available in PMC: 2017 Nov 3.
Published in final edited form as: J Nanomed Nanotechnol. 2017 Aug 31;8(4):456. doi: 10.4172/2157-7439.1000456

Figure 3.

Figure 3

Dark field microscopy images of HEI-OC1 cells. Targeted GNPs (0.25 mg/ml) (C) or untargeted GNPs (0.25 mg/ml) (B) were added to differentiated HEI-OC1 cells. The treated cells were then incubated for 24 hours, alongside control HEI-OC1 cells where GNPs were not added (A), to allow the nanoparticles to bind to the cells. The dark field images clearly show that much greater light scattering was observed with targeted GNPs (C) than with the other samples. This strongly suggests that the GNPs bound specifically to the HEI-OC1 cells: presumably to prestin.