Figure 8.
Detection of liposomal iodine in cochlear CT imaging after in vivo application of liposomal iodine. Liposomal iodine was applied in vivo into mouse cochleae. After dissection, the micro-CT imaging system was used to scan the untreated control (A) and liposomal iodine-treated (B) cochleae. The magnified image of the liposomal iodine-treated cochlea (C) clearly shows the presence of the liposomal iodine, which had collected near the Organ of Corti. This was not detected in the control group (A). Although the liposomal iodine was detected inside the test cochlea, it did not enter the cells in sufficient quantities to enhance CT soft tissue imaging.