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. 2015 Oct 28;4:351–356. doi: 10.1016/j.bbrep.2015.10.012

Fig. 2.

Fig. 2.

SMN protein expression in salbutamol-treated SMA fibroblast cells. Salbutamol concentrations used in this study were 0.005, 0.05 and 0.5 µM. Measurement time points were 0 h, 1 h, 6 h, 8 h, 12 h, 24 h and 36 h. (A) Western blotting analysis of SMN protein in SMA fibroblast cells. (B) Relative SMN protein levels in salbutamol-treated SMA fibroblast cells. Salbutamol increased SMN protein levels in dose- and time-dependent manners. (C) Effect of PKA inhibitor on SMN protein levels. PKA inhibitor, 14–22 amide cell-permeable, myristoylated, completely repressed the salbutamol (0.5 µM)-induced increase of SMN protein.