Fig. 6.

The graph depicts the percentage (%) of transfected muscle fibers (A) and representative cross-sections (B) in the mid-belly portion of the Tibialis anterior muscle of Sprague-Dawley rats (n=24). All rats were pre-treated with hyaluronidase (0.56 U/g b.w.) 1 min prior to plasmid (0.8 µg/g b.w.) injection in vehicle (1.5 µl/g b.w.) delivered by 7 evenly spaced injections and electroporated immediately after. Muscles were harvested 1 week after transfection (B, n=4) or after an additional 5 weeks of sedentary life (S, n=11) or exercise training on a motorized treadmill (T, n=11). The data are presented as mean±SE.