Dose 1 coverage (6 weeks) |
0.88 |
0.66, 1 |
[35] |
Dose 2 coverage (10 weeks) |
0.80 |
0.60, 1 |
[35] |
Dose 3 coverage (14 weeks) |
0.72 |
0.54, 0.9 |
[35] |
Efficacy of vaccine against severe infection (δsev) |
0.536 |
0.35, 0.669 |
[15] |
Efficacy of vaccine against symptomatic infection (δsx) |
0.346 |
0.216, 0.453 |
[15] |
Efficacy of vaccine against any infection (δany) |
0.304 |
0.1988, 0.38 |
Based on ratio of efficacy of prior natural infection against any infection to efficacy of prior natural infection against severe infection[28] |
Proportion of efficacy (pd) conferred by d = 0, 1, 2, 3 doses |
0, 0.82, 0.84, 1 |
Low: 0, 0.62, 0.64, 1; High: 0, 1, 1, 1 |
[36] |
Annual rate of waning of vaccine efficacy |
0.086 |
0, 0.2 |
[8, 37] |
Risk of intussusception |
0.00003 |
|
[38] |
Case fatality of intussusception |
0.25 |
|
Assumption |