. Author manuscript; available in PMC: 2018 Feb 3.

Published in final edited form as: J Hum Genet. 2017 Aug 3;62(11):979–988. doi: 10.1038/jhg.2017.76

Table 5.

LD regression results for NLR, PLR and the blood cell counts.

	NLR	PLR	Neutrophil	Lymphocyte	Platelet
Mean of χ²	0.997	1.014	1.009	1.021	1.034
λ GC	0.996	1.024	1.017	1.018	1.027
H² (se)	0.0239(0.0816)	0.1412(0.0844)	0.1537(0.1011)	0.1912(0.0895)	0.3615(0.0877)
Intercept (se)	0.9943(0.0067)	0.9994(0.0059)	0.9932(0.0081)	1.0011(0.0069)	0.9974(0.0065)

Mean of χ²: the mean of χ² statistic of markers in the GWAS sample. The difference between this value and the intercept indicates the contribution of polygenicity to the statistical inflation. λ GC: the lambda genomic control inflation factor. H² (se): the estimated SNP heritability based on LD score regression with (standard error). Intercept (se) the regression intercept with (standard error), where the value minus one, indicates the contribution of confounding in the studied sample.