Table 1.
Clinical characteristics of patients with lipodystrophies
| All subjects (n=32 ) | Generalized lipodystrophy (n=13) | Partial lipodystrophy (n=19) | P (generalized vs. partial) | |
|---|---|---|---|---|
| Age (years) | 30 (21–38) | 21 (15–30) | 34 (28–45) | 0.01 |
| Gender (F/M) | 24/8 | 9/4 | 15/4 | 0.68 |
| Glucose (mg/dL) | 143 (114–202) | 144 (108–224) | 142 (116–206) | 0.67 |
| HbA1c (%) | 8.2 (6.2–9.5) | 7.0 (6.0–10.7) | 8.4 (6.2–9.3) | 0.98 |
| Triglyceride (mg/dL) | 372 (223–659) | 581 (310–1268) | 342 (210–544) | 0.47 |
| Total cholesterol (mg/dL) | 181 (159–235) | 169 (145–257) | 195 (164–230) | 0.15 |
| LDL cholesterol (mg/dL) | 98 (68.2–117) | 91 (60–107) | 104 (72–126) | 0.47 |
| HDL cholesterol (mg/dL) | 28 (22–37) | 27 (19–31) | 32 (24–40) | 0.25 |
| Creatinin (mg/dL) | 0.6 (0.5–0.9) | 0.5 (0.4–0.7) | 0.7 (0.6–0.9) | 0.031 |
| ALT (IU/L) | 24 (18–44) | 29 (18–52) | 23 (18–38) | 0.56 |
| Leptin (ng/mL) | 1.2 (0.4–4.5) | 0.3 (0.1–0.7) | 3.4 (1.5–6.6) | 0.001 |
| Adiponectin (μg/mL) | 2.7 (0.9–5.3) | 0.7 (0.5–3.8) | 3.4 (1.8–8.6) | 0.031 |
Data are presented as median (IQR).
F, female; M, male; HbA1c, glycated hemoglobin A1c; LDL, low-density lipoprotein; HDL, high-density lipoprotein; ALT, alanine aminotransferase.