Table 2.
Residual adipose tissue characteristics of patients with various subtypes of lipodystrophy
| Periarticular region | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|||||||||||||||||
| Head and neck | Knee | Hip | |||||||||||||||
|
|
|
|
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| Scalp | Retro-orbital | Buccal | Masticator | Para-pharyngeal | Ear lobe | Palms | Soles | Breasts | External genital | İnfra-patellar | Supra-patellar | Popliteal | Acetabular roof | Extra-articular | |||
| Generalized lipodystrophies | CGL | CGL1 | + | + | R | + | R | + | R | + | R | R | + | + | R | + | + |
| CGL2 | − | − | − | − | − | − | − | − | − | R | R | R | R | + | − | ||
| CGL4 | − | + | R | R | R | − | − | − | − | − | R | − | R | − | − | ||
| AGL | − | − | − | − | − | − | − | − | − | − | − | − | − | − | − | ||
|
| |||||||||||||||||
| Partial lipodystrophies | FPLD | LMNA | + | + | + | + | + | + | + | + | +/R | + | + | + | + | + | + |
| PPARG | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | ||
| Negative | + | + | + | + | + | + | R | R | R | + | + | R | − | − | − | ||
| APL | − | + | − | − | − | − | − | R | − | R | + | + | + | + | + | ||
R, reduced; CGL, congenital generalized lipodystrophy; AGL, acquired generalized lipodystrophy; FPLD, familial partial lipodystrophy; LMNA, lamin A/C; PPARG, peroxisome proliferator-activated receptor gamma; APL, acquired partial lipodystrophy.