Table 2.

Comparison of sleep disturbance and fatigue between OAB and controls

	OAB (n = 51)	Controls (n = 30)	p-value (adjusted for age and sex)	p-value (adjusted for age, sex, AND NOCTURIA)
Sleep measures (over past 7 days)
PROMIS-8b (sleep disturbance, T-score)	54.3 ± 10.3	43.8 ± 9.2	<0.001	0.213
% with PROMIS-8b > 50	68.6%	23.3%	<0.001	0.053
Odds ratio of having PROMIS-8b > 50 in OAB	OR = 8.5 95% CI [2.8, 25.6]
My sleep was restlessa	3.1 ± 1.3	1.7 ± 1.0	<0.001	0.075
I was satisfied with my sleepb	3.4 ± 1.3	2.3 ± 1.3	<0.001	0.190
My sleep was refreshingb	3.2 ± 1.3	2.3 ± 1.3	0.005	0.612
I had difficulty falling asleepa	2.5 ± 1.4	1.8 ± 1.0	0.014	0.790
I had trouble staying asleepa	3.1 ± 1.4	1.9 ± 1.0	<0.001	0.627
I had trouble sleepinga	3.0 ± 1.4	1.9 ± 0.9	<0.001	0.543
I got enough sleepb	3.0 ± 1.2	2.1 ± 1.0	<0.001	0.430
My sleep quality wasc	3.1 ± 1.1	2.0 ± 0.9	<0.001	0.104
Fatigue measures (over past 7 days)
PROMIS-7a (fatigue, T-score)	54.7 ± 9.6	46.0 ± 6.4	<0.001	0.014
% with PROMIS-7a > 50	62.7%	26.7%	0.005	0.017
Odds ratio of having PROMIS-7a > 50 in OAB	OR = 4.3 95% CI [1.5, 11.8]
How often did you feel tired?d	3.3 ± 1.1	2.5 ± 0.7	0.002	0.040
How often did you experience extreme exhaustion?d	2.6 ± 1.2	1.5 ± 0.6	<0.001	0.039
How often did you run out of energy?d	2.7 ± 1.1	1.8 ± 0.8	0.001	0.006
How often did your fatigue limit you at work (include work at home)?d	2.5 ± 1.1	1.5 ± 0.8	<0.001	0.001
How often were you too tired to think clearly?d	2.3 ± 1.1	1.4 ± 0.7	<0.001	0.039
How often were you too tired to take a bath or shower?d	2.0 ± 1.1	1.4 ± 0.8	0.023	0.335
How often did you have enough energy to exercise strenuously?e	3.6 ± 1.2	3.3 ± 1.3	0.496	0.253

^a1 = Not at all, 2 = A little bit, 3 = Somewhat, 4 = Quite a bit, 5 = Very much

^b5 = Not at all, 4 = A little bit, 3 = Somewhat, 2 = Quite a bit, 1 = Very much

^c5 = Very poor, 4 = Poor, 3 = Fair, 2 = Good, 1 = Very good

^d1 = Never, 2 = Rarely, 3 = Sometimes, 4 = Often, 5 = Always

^e5 = Never, 4 = Rarely, 3 = Sometimes, 2 = Often, 1 = Always