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. 2017 Oct 30;11:3137–3144. doi: 10.2147/DDDT.S150656

Figure 2.

Figure 2

Mechanism of action of mepolizumab. Mepolizumab binds with high affinity to IL-5, thus preventing its interaction with the IL-5 receptor expressed by eosinophils and, to a lesser extent, also by basophils.

Abbreviation: IL-5, interleukin-5.