Table S2.
The association between long chain unsaturated fatty acid and FEV1/FVC decline (%) in the LSC (n=1,499)a
| Nutrient (U/day) | Time
|
Nutrients
|
Time × nutrients
|
||
|---|---|---|---|---|---|
| Estimate (SE)b | Estimate (SE) | P-value | Estimate (SE) | P-value | |
| Eicosenoic fatty acid (135 mg) | −0.47 (0.02) | −0.048 (0.11) | 0.67 | 0.032 (0.012) | 0.0081 |
| EPA (100 mg) | −0.44 (0.01) | 0.010 (0.052) | 0.85 | 0.019 (0.006) | 0.0030 |
| DPA (20 mg) | −0.46 (0.02) | −0.003 (0.087) | 0.98 | 0.032 (0.011) | 0.0028 |
| DHA (150 mg) | −0.46 (0.02) | −0.037 (0.088) | 0.67 | 0.031 (0.011) | 0.0031 |
| EPA + DPA + DHA (310 mg) | −0.45 (0.02) | −0.007 (0.083) | 0.94 | 0.030 (0.010) | 0.0028 |
| EPA + DHA (290 mg) | −0.45 (0.02) | −0.006 (0.082) | 0.94 | 0.030 (0.010) | 0.0028 |
Notes: EPA, eicosapentaenoic fatty acid 20:5n3; DPA, docosapentaenoic fatty acid 22:5n3; DHA, docosahexaenoic fatty acid 22:6n3; eicosenoic fatty acid 20:1n9.
a
IQR is used for calculating the estimate and SE. Association analysis in the LSC was conducted based on longitudinal spirometry data using linear mixed effects model with adjustment for important covariates.
b
P<0.0001.
Abbreviations: FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LSC, Lovelace Smokers cohort; SE, standard error; IQR, interquartile range.