Table 1.

Properties of PoP liposomes used in this study.

Formulation	Dox loading (%)	Zeta Potential (mV)	Size (nm)	Polydispersity (PDI)	Light release of Dox T50% (sec)	Light release of Dox T90% (sec)	% Dox release in serum (1 hr)
Neutral	95 ± 3	-0.9 ± 0.9	101 ±2	0.02 ± 0.02	19 ± 0.6	76 ± 9	6 ± 0.4
5% DOTAP	98 ± 2	27.1 ± 0.8	111 ±7	0.05 ± 0.01	13 ± 2.3	40 ± 12	4 ± 0.3
10% DOTAP	96 ± 4	33.9 ± 1.4	101 ±1	0.08 ± 0.01	9 ± 0.6	17 ± 1	7 ± 0.4
20% DOTAP	98 ± 2	47.9 ± 2.3	109 ± 10	0.06 ± 0.03	5 ± 0.6	11 ± 3	7 ± 0.6
30% DOTAP	99 ± 2	47.3 ± 1.2	99 ± 3	0.07 ± 0.02	7 ± 0.0	15 ± 1	34 ± 0.9

Data show mean +/- standard deviation for 3 separate measurements.

Light triggered release were performed at 250 mW/cm² in 50% bovine serum at 37°C. Serum stability were performed in 50% bovine serum at 37°C. Mean±s.d. for n=3.