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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Curr Genet. 2017 May 16;63(6):989–995. doi: 10.1007/s00294-017-0707-6

Fig. 2.

Fig. 2

Outstanding questions about polarized mRNA transport in C. albicans hyphae. 1 Are there cis-acting sequences or structures (*) on mRNAs that direct localization? 2 What protein(s) help export asymmetrically localized mRNAs from the nucleus? 3 Do RNA-binding proteins repress translation of mRNAs during transport? 4 Are mRNA transport complexes associated with membranes? CaSec2 protein and mRNA associate with secretory vesicles, but CaShe3 is not part of this complex (Caballero-Lima, et al. 2014). 5 What proteins depend on directional mRNA transport for their asymmetric localization in hyphae? Italics and question marks indicate proteins and structures hypothesized to play a role in CaShe3-mediated mRNA transport.