Table 1. SPR summary of anti-TNF-α/IL-17A bsAb, anti-TNF-α mAb and anti-IL-17A mAb.

Antibody	Antigen	kon, (mol/L-1)s-1	koff, s-1	Rmax	KD, mol/L
Anti-IL-17A mAb	IL-17A	4.2×105	7.0×10-5	43.6	1.7×10-10
	TNF-α	No Binding
	IL-17A+TNF-α	4.4×105	7.5×10-5	43.1	1.7×10-10
Anti-TNF-α mAb	IL-17A	No binding
	TNF-α	4.7×105	1.7×10-4	57.8	3.7×10-10
	IL-17A+TNF-α	4.7×105	1.7×10-4	60.3	3.7×10-10
BsAb	IL-17A	4.0×105	7.9×10-5	30.6	2.0×10-10
	TNF-α	4.7×105	1.6×10-4	59.1	3.3×10-10
	IL-17A+TNF-α	4.6×105	1.2×10-4	88.6	2.5×10-10