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The tumor volume and weight were measured by ruling, capacity measurement and weighting (A) after MCF-7 and its ING5 transfectants were subcutaneously injected. Immunohistochemistry was employed for the detection of ING5 expression, ki-67 for proliferation and LC-3B for autophagy, while TUNEL for apoptotic signal (B). *p < 0.05, compared with the transfectants.
