Table 1. ING5 expression in breast carcinogenesis and subsequent progression.
Groups | Nuclear ING5 expression | Cytoplasmic ING5 expression | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
n | – | + | ++ | +++ | PR(%) | – | + | ++ | +++ | PR(%) | |
Normal tissue | 91 | 1 | 4 | 10 | 76 | 98.9 | 49 | 29 | 8 | 5 | 46.2 |
Fibroadenoma | 61 | 5 | 9 | 21 | 26 | 91.8a | 11 | 28 | 22 | 0 | 82.0a |
Adenomatosis | 110 | 4 | 14 | 38 | 54 | 96.4a,b | 29 | 56 | 23 | 2 | 73.6a |
Primary cancer | 260 | 24 | 60 | 101 | 75 | 90.8a | 54 | 127 | 66 | 13 | 79.2a |
Metastatic cancer in lymph node | 55 | 11 | 22 | 16 | 6 | 80.0b | 9 | 31 | 13 | 2 | 83.6 |
ap < 0.05, compared with normal tissue; bp < 0.05, compared with primary cancer; PR, positive rate.