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. 2017 May 17;8(47):81953–81966. doi: 10.18632/oncotarget.17918

Table 3. Relationship between ING5 expression and clinicopathological features of the non-basal triple negative breast cancer.

Clinicopathological
Features
n Nuclear ING5 expression Cytoplasmic ING5 expression
+ ++ +++ PR(%) p + ++ +++ PR(%) p
Age (years)
 < 45 29 4 7 10 8 86.2 0.299 0 20 8 1 100.0 0.484
 ≥ 45 139 10 25 62 42 92.8 26 63 43 7 81.3
Tumor size(cm)
 < 2.5 87 9 18 36 24 89.7 18 47 21 1 79.3
 ≥ 2.5 74 5 14 33 22 93.2 0.495 7 33 27 7 90.5 0.001
Pathological classification
 Invasive ductal cancer 142 13 27 60 42 90.2 0.634 21 71 43 7 85.2 0.136
 Invasive lobular cancer 9 1 2 4 2 88.9 4 3 1 1 55.6
Lymphatic vessel invasion
 + 19 2 3 8 6 89.5 0.701 1 12 4 2 94.7 0.569
 – 54 0 14 21 19 100.0 9 26 19 0 83.3
Lymph node metastasis
 + 77 4 15 35 23 94.8 0.486 11 38 24 4 85.7 0.426
 – 79 10 14 32 23 87.3 15 39 21 4 81.0
TNM Staging
 I–II 51 10 9 23 9 80.4 9 22 15 5 82.4
 III–IV 7 1 0 4 2 85.7 0.296 2 2 3 0 71.4 0.727
ER expression
 + 104 8 19 50 27 92.3 0.931 16 52 31 5 84.6 0.905
 – 49 6 9 19 15 87.8 7 26 14 2 85.7
PR expression
 + 90 6 16 45 23 93.3 0.743 14 46 26 4 84.4 0.800
 – 63 8 12 24 19 87.3 9 32 19 3 85.7
Her2 expression
 + 93 9 17 42 25 90.3 0.712 15 50 26 2 83.9 0.201
 – 58 5 10 26 17 91.4 8 27 18 5 86.2
p53 expression
 + 63 1 11 25 26 98.4 0.045 10 33 18 2 84.1 0.896
 – 32 2 8 15 7 93.8 3 20 8 1 90.6
Ki-67 percentage (%)
 < 50 135 13 23 61 38 90.4 0.771 21 68 41 5 84.4 0.354
 ≥ 50 19 1 4 8 6 94.7 2 9 6 2 89.5

PR , positive rate; TNM, tumor node metastasis; ER, estrogen receptor; PR, progesterone receptor.