Table 4. Relationship between ING5 expression and clinicopathological features of the triple-negative breast cancer.
Clinicopathological features | Nuclear ING5 expression | Cytoplasmic ING5 expression | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | – | + | ++ | +++ | PR(%) | p | – | + | ++ | +++ | PR(%) | p | |
Age (years) | |||||||||||||
< 45 | 29 | 3 | 8 | 8 | 10 | 89.7 | 0.444 | 11 | 16 | 2 | 0 | 62.1 | 0.044 |
≥ 45 | 63 | 7 | 20 | 21 | 15 | 88.9 | 17 | 28 | 13 | 5 | 73.0 | ||
Tumor size (cm) | |||||||||||||
< 2.5 | 5 | 0 | 1 | 1 | 3 | 100.0 | 0.251 | 2 | 1 | 1 | 1 | 60.0 | 0.907 |
≥ 2.5 | 10 | 1 | 4 | 2 | 3 | 90.0 | 2 | 4 | 1 | 3 | 80.0 | ||
Lymph node metastasis | |||||||||||||
+ | 38 | 6 | 11 | 10 | 11 | 84.2 | 0.439 | 16 | 15 | 3 | 4 | 57.9 | 0.107 |
– | 53 | 4 | 16 | 19 | 14 | 92.5 | 11 | 29 | 12 | 1 | 79.2 | ||
Distant metastasis | |||||||||||||
+ | 10 | 2 | 5 | 3 | 0 | 80.0 | 0.026 | 3 | 6 | 1 | 0 | 70.0 | 0.605 |
– | 82 | 9 | 22 | 26 | 25 | 89.0 | 25 | 38 | 14 | 5 | 69.5 | ||
TNM staging | |||||||||||||
I–II | 67 | 8 | 16 | 20 | 23 | 88.1 | 0.056 | 21 | 29 | 14 | 3 | 68.7 | 0.661 |
III–IV | 24 | 2 | 11 | 9 | 3 | 91.7 | 7 | 14 | 1 | 2 | 70.8 |
PR, positive rate; TNM, tumor node metastasis.