Table 2. Comparison of the number and function of lymphocytes.
Test items of lymphocyte | Test results | ||
---|---|---|---|
Pre-treatment (n=61) | Cryoablation (n=26) | Cryo-NK (n=35) | |
Number (cell/μL): | |||
Total T cell | 1456 ± 52 | 1623 ± 67* | 1812 ± 91** |
CD8+T cell | 621 ± 7 | 727 ± 29* | 754 ± 11** |
CD4+T cell | 735 ± 30 | 821 ± 35* | 856 ± 33** |
NK cell | 372 ± 31 | 552 ± 63* | 786 ± 73*** |
B cell | 309 ± 11 | 465 ± 33** | 551 ± 41* |
Function (pg/mL): | |||
IL-2 | 9.9 ± 3.4 | 17.6 ± 3.5** | 23 ± 4.6*** |
TNF-β | 3.8 ± 2.2 | 9.8 ± 2.5*** | 14 ± 2.5*** |
IFN-γ | 4.8 ± 3.3 | 10.8 ± 3.6** | 16 ± 37*** |
IL-4 | 10.2 ± 2.1 | 10.1 ± 3.4 | 11.2 ± 3.6 |
IL-6 | 13.2 ± 3.9 | 15.2 ± 4.5 | 15.5 ± 7.9** |
IL-10 | 9.2 ± 2.7 | 9.3 ± 2.3 | 10.1 ± 3.4 |
Note: All cell subsets and cytokines were analyzed via a Dunnett’s multiple comparison test (one-way ANOVA). NK cell, natural killer cell; IL, interleukin; TNF, tumor necrosis factor; IFN, interferon *P < 0.05; **P < 0.01; ***P < 0.001.