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. 2017 May 23;8(47):81978–81993. doi: 10.18632/oncotarget.18184

Table 1. The clinicopathological characteristics of the retrospective study subgroup.

Censored patients n (%) Nonsurvivors n (%) Median survival time (interquartile range) P
Age
 < 65 105 (38.6) 54 (19.9) 365 (192, 365) 0.692
 ≥ 65 72 (26.5) 41 (15.1) 335 (124, 365)
Gender
 Male 98 (36) 65 (23.9) 313 (141, 365) 0.036
 Female 79 (29) 30 (11) 365 (214, 365)
Current smoking
 No 102 (37.5) 36 (13.2) 365 (244, 365) 0.002
 Yes 75 (27.6) 59 (21.7) 286.5 (112.5, 365)
PS
 0–1 143 (52.6) 68 (25) 365 (192, 365) 0.082
 2 34 (12.5) 27 (9.9) 294 (95.5, 365)
Tumor location
 Right lung 96 (35.3) 61 (22.4) 365 (162, 365) 0.112
 Left lung 81 (29.8) 34 (12.5) 365 (172, 365)
Pathological type
 Squamous carcinoma 34 (12.5) 16 (5.9) 349 (135.5, 365) 0.631
 Adenocarcinoma and adenosquamous carcuinoma 143 (52.6) 79 (29) 365 (170.5, 365)
TNM Stage
 IVa 67 (24.6) 25 (9.2) 365 (193.75, 365) 0.055
 IVb 110 (40.4) 70 (25.7) 336 (146.75, 365)
T stage
 T1–T2 41 (15.1) 17 (6.3) 365 (201.25, 365) 0.312
 T3–T4 136 (50) 78 (28.7) 365 (157.75, 365)
N stage
 N0–N2 85 (31.3) 30 (11) 365 (212, 365) 0.009
 N3 92 (33.8) 65 (23.9) 313 (154.5, 365)
M stage
 1a 51 (18.8) 16 (5.9) 365 (233, 365) 0.029
 1b–1c 126 (46.3) 79 (29) 335 (124, 365)
Organ metastasis counts
 < 2 69 (25.4) 21 (7.7) 365 (227.5, 365) 0.005
 ≥ 2 108 (39.7) 74 (27.2) 326 (144.25, 365)
Therapy
 Chemotherapy 141 (51.8) 84 (30.9) 365 (164, 365) 0.068
 Targeted drugs 36 (13.2) 11 (4.0) 365 (163, 365)
CEA
 < 5 ng/ml 70 (25.7) 45 (16.5) 314 (125, 365) 0.213
 ≥ 5 ng/ml 107 (39.3) 50 (18.4) 365 (211.5, 365)

Abbreviations: PS, Performance Status; CEA, carcinoembryonic antigen.