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. 2017 May 30;8(47):82006–82026. doi: 10.18632/oncotarget.18299

Figure 10. Low conductance ER Ca2+ leak assay demonstrates that IMP1, unlike PSEN1, is not a ion channel.

Figure 10

(A) Ionomycin (IO)-induced Ca2+ signal curves in PSEN1-/-/PSEN2-/-, mIMP1-/- and matching wild type control MEF lines. (B) The histogram presents the mean size of IO-induced Ca2+ pool (±SD) in PSEN1-/-/PSEN2-/-, mIMP1-/- and matching control MEF lines. ‘*’ p<0.05 by ANOVA – significant Ca2+ pool changes compared to NC. The number of cells analyzed is indicated (n).