Skip to main content
. 2017 May 30;8(47):82006–82026. doi: 10.18632/oncotarget.18299

Figure 14. No rescue of Ce-imp-2 knockout phenotypes was found by constructs producing Ce-IMP-2 G350K, P417L mutant proteins.

Figure 14

If none of the 20-30 roller phenotype (transgenic marker) worms, progeny of injected Ce-imp-2+/- worms, displayed rescue phenotype on Ce-imp-2-/- background, then ∼200 single worms, synchronized mixed viable progeny of several transgenic Ce-imp-2+/- animals, were analyzed. In addition, for G350K strain #1, we checked phenotypes of Ce-imp-2+/+ animals progeny. The rate of the losing transgenic status was estimated as percentage of non-roller wild type phenotype animals/total number of wild type phenotype animals. P-value significance codes: ‘**’ <0.01, ‘*’ <0.05.