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(A) Immunohistochemistry for Cox-2 shows abundant expression in high-grade glioma (BT2011064, BT2012104), with lower expression in low-grade glioma (BT2013034) and infiltrated brain. (B, C) Analysis of expression data from The Cancer Genome Atlas (TCGA). Cox-2 mRNA levels increase with increasing glioma grade and is enriched in the mesenchymal subgroup. Data are represented as mean ± SEM.
