(A) OTUs that were significantly correlated with clinical parameters. (B) Correlation analysis between identified genera and clinical parameters. Correlation analyses between relative abundance (%) of specific OTU and genus and clinical parameters were performed by using Spearman’s correlation analyses. n=10, in each group. (*) represents the specific OTU and genus whose abundance were significantly correlated with certain clinical parameters. The color of the spots in the right panel represents R-value of Spearman’s correlation between the OTU and genus and clinical parameters. OTU, operational taxonomic unit; BW, body weight; BMI, body mass index; BMI1, BMI at the beginning of 1st trimester; BMI2, body mass index at the end of 3rd trimester; BW1, body weight at the beginning of 1st trimester; BW2, body weight at the end of 3rd trimester; IGF-1, insulin-like growth factor-1.