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. 2017 Jul 27;8(47):82459–82474. doi: 10.18632/oncotarget.19614

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Copyright: © 2017 Langevin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Venn diagram of differential exosomal miRNA cargo for each of 4 head and neck squamous cell carcinoma (HNSCC) cell lines relative to those derived from primary non-pathologic oral epithelial control cells; numbers in each segment represent the respective number of overlapping differentially secreted exosomal miRNA. (B) Exosomal miRNA that were differentially secreted in exosomes by all 4 HNSCC cell lines (n = 32) relative to the oral epithelial control cells. Downregulated exosomal miRNA (n = 13) are presented in green and upregulated miRNA (n = 19) are presented in red.