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. 2017 Aug 2;8(47):82754–82772. doi: 10.18632/oncotarget.19787

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Copyright: © 2017 Iesato et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) p53 expression in the clinical thyroid specimens. Representative images of immunohistochemical analysis of p53 expression are shown; normal thyroid gland (NT) (a), adenomatous goiter (AG) (b), follicular adenoma (FA) (c), papillary thyroid cancer (PTC) (d; positive, e; negative), poorly differentiated thyroid cancer (PDTC) (f; positive, g; negative), and anaplastic thyroid cancer (ATC) (h; positive, i; negative). Scale bar = 50 μm. (B) The ratio of PATZ1 positive tumors in differentiated thyroid cancer (DTC), PDTC, and ATC according to p53 status. The percentage of nuclear PATZ1 positive tumors (filled bar) and that of PATZ1 negative tumors (grid bar) are shown in the bar chart.