Table 3. Expression of nuclear p53 in thyroid tumors.
| Histological type | NT (N = 50) |
AG (N = 18) |
FA (N = 5) |
PTC (N = 39) |
FTC (N = 8) |
PDTC (N = 12) |
ATC (N = 28) |
|
|---|---|---|---|---|---|---|---|---|
| p53 | positive (%) |
0 (0) |
0 (0) |
2 (40.0) |
6 (15.4) |
0 (0) |
8 (66.7) |
13*# (46.4) |
| negative (%) |
50 (100) |
18 (100) |
3 (60.0) |
33 (84.6) |
8 (100) |
4 (33.3) |
15 (53.6) |
NT; normal thyroid gland, AG; adenomatous goiter, FA; follicular adenoma, PTC; papillary thyroid cancer, FTC; follicular thyroid cancer, PDTC; poorly differentiated thyroid cancer, ATC; anaplastic thyroid cancer.
*p < 0.01 vs. NT/AG, #p < 0.01 vs. DTC (PTC/FTC).