Table 1. Univariate and multivariate Cox regression analysis of overall survival in archival ccRCC patients.
Variables | No. of patients (%) | Univariate analysis | Multivariate analysis | |||||
---|---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |||
Sex | 0.508 | 0.889 | ||||||
Female | 28(42.42%) | Male vs female | 0.749 | 0.317-1.765 | 1.069 | 0.419-2.725 | ||
Male | 38(57.58%) | |||||||
Age (y) | 0.936 | 0.515 | ||||||
≤60 | 38(57.58%) | >60 vs ≤60 | 1.036 | 0.439-2.442 | 1.356 | 0.541-3.399 | ||
>60 | 28(42.42%) | |||||||
Tumor size (cm) | 0.834 | 0.470 | ||||||
≤4 | 20(30.30%) | >4 vs ≤4 | 0.960 | 0.655-1.407 | 1.205 | 0.726-2.002 | ||
>4 | 32(48.48%) | |||||||
Location | 0.385 | 0.267 | ||||||
Left | 30(45.45%) | Right vs Left | 0.684 | 0.290-1.611 | 0.601 | 0.245-1.476 | ||
Right | 36(54.55%) | |||||||
Fuhrman grade | 0.237 | 0.075 | ||||||
I, II | 45(68.18%) | III, IV vs I, II | 1.462 | 0.779-2.747 | 1.995 | 0.933-4.264 | ||
III, IV | 18(27.27%) | |||||||
pT status | 0.002 | 0.026 | ||||||
pT1/T2 | 51(77.30%) | pT1/T2 vs pT3/T4 | 4.509 | 1.751-11.611 | 3.524 | 1.164-10.674 | ||
pT3/T4 | 15(22.70%) | |||||||
miR-93 expression | 0.002 | 0.008 | ||||||
Low | 34(51.52%) | High vs Low | 5.281 | 1.886-14.786 | 4.619 | 1.488-14.338 | ||
High | 32(48.48%) |
HR, hazard ratio.