Table 4. Genotypic model analysis of relationship between rs2274755 and ONFH risk.
| Model | Genotype | Control | Case | Without adjustment | With adjustment | AIC | BIC | ||
|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | P | ||||||
| Codominant | G/G | 364 (71.8%) | 457 (78.1%) | 1 | 0.053 | 1 | 0.04* | 1508.4 | 1523.4 |
| G/T | 133 (26.2%) | 120 (20.5%) | 0.72 (0.54-0.95) | 0.70 (0.52-0.93)* | |||||
| T/T | 10 (2%) | 8 (1.4%) | 0.64 (0.25-1.63) | 0.65 (0.25-1.68) | |||||
| Dominant | G/G | 364 (71.8%) | 457 (78.1%) | 1 | 0.016* | 1 | 0.011* | 1506.4 | 1516.4 |
| G/T-T/T | 143 (28.2%) | 128 (21.9%) | 0.71 (0.54-0.94) | 0.70 (0.52-0.92)* | |||||
| Recessive | G/G-G/T | 497 (98%) | 577 (98.6%) | 1 | 0.43 | 1 | 0.47 | 1511.6 | 1521.6 |
| T/T | 10 (2%) | 8 (1.4%) | 0.69 (0.27-1.76) | 0.70 (0.27-1.83) | |||||
| Overdominant | G/G-T/T | 374 (73.8%) | 465 (79.5%) | 1 | 0.026* | 1 | 0.018* | 1507.3 | 1517.3 |
| G/T | 133 (26.2%) | 120 (20.5%) | 0.73 (0.55-0.96) | 0.71 (0.53-0.94)* | |||||
| Log-additive | — | — | — | 0.74 (0.57-0.95) | 0.017* | 0.72 (0.56-0.94)* | 0.013* | 1506.5 | 1516.5 |
p* ≤ 0.05 indicates statistical significance.
p values were calculated by Wald test by unconditional logistic regression adjusted for age and gender.
AIC = Akaike Information Criterion.
BIC = Bayesian Information Criterion.